Spiro trienones are an important class of compounds in synthetic organic chemistry, known for their complex three-dimensional structures and potential applications in pharmaceuticals and materials science. Bi-aryl ynones, characterized by the conjugation of an alkyne with two aryl rings, have emerged as a highly versatile structural motif for the construction of spiro trienones. This review provides a comprehensive overview of the synthetic approaches to spiro trienones using bi-aryl ynones, exploring their struc- tural features, reactivity, and the underlying mechanisms of their transformations. The review also discusses the broad scope of these reactions and highlights recent ad- vances that have expanded the utility of bi-aryl ynones in organic synthesis. Potential applications of spiro trienones in drug discovery and materials science are also discussed, along with future directions for research in this area.

Articles Details

NAMES:

ONLINE ISSN:2456-8244

Keywords: Trienonesn spiro trienonesn Ynonesn Bi-aryl , Cyclization

DOI:

Abstract FullText PDF

REFERENCES

 Smith, J. A., & Johnson, L. K. (2023). 
"Palladium-Catalyzed Cyclizations of Bi- Aryl 
Ynones: A Route to Spirocyclic Compounds."